Ke-Da Yu Selected Research

Therapeutics

1/2024	Optimising first-line subtyping-based therapy in triple-negative breast cancer (FUTURE-SUPER): a multi-cohort, randomised, phase 2 trial.
1/2024	Rational and trial design of FASCINATE-N: a prospective, randomized, precision-based umbrella trial.
1/2022	Determining the Optimal (Neo)Adjuvant Regimen for Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Regarding Survival Outcome: A Network Meta-Analysis.
1/2022	De-escalation of five-year adjuvant endocrine therapy in patients with estrogen receptor-low positive (immunohistochemistry staining 1%-10%) breast cancer: Propensity-matched analysis from a prospectively maintained cohort.
1/2022	Breast Cancer Vaccines: Disappointing or Promising?
10/2021	Estrogen receptor-low breast cancer: Biology chaos and treatment paradox.
3/2020	Association of adjuvant aromatase inhibitor with cataract risk in postmenopausal women with breast cancer.
1/2018	Genomic Landscape and Endocrine-Resistant Subgroup in Estrogen Receptor-Positive, Progesterone Receptor-Negative, and HER2-Negative Breast Cancer.
10/2016	Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer.
3/2016	Comprehensive transcriptome analysis identifies novel molecular subtypes and subtype-specific RNAs of triple-negative breast cancer.

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Ke-Da Yu Research Topics

Disease

74	Breast Neoplasms (Breast Cancer) 01/2024 - 06/2007
35	Neoplasms (Cancer) 01/2024 - 02/2011
20	Triple Negative Breast Neoplasms 01/2024 - 05/2013
8	Neoplasm Metastasis (Metastasis) 01/2022 - 02/2011
6	Carcinogenesis 01/2024 - 07/2009
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2015 - 03/2013
2	Cardiotoxicity 01/2022 - 01/2014
2	Carcinoma (Carcinomatosis) 01/2017 - 01/2013
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2015 - 05/2011
2	Obesity 01/2015 - 01/2012
2	Unilateral Breast Neoplasms 01/2014 - 01/2011
2	Residual Neoplasm 12/2013 - 05/2013
2	Macular Degeneration (Age-Related Maculopathy) 01/2012 - 10/2011
1	Neutropenia 01/2024
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Infertility (Sterility) 10/2021
1	Premature Menopause 10/2021
1	Cataract (Cataracts) 03/2020
1	Ovarian Epithelial Carcinoma 09/2015
1	Lymphatic Metastasis 09/2014
1	Hypoxia (Hypoxemia) 06/2014

Drug/Important Bio-Agent (IBA)

13	Hormones (Hormone)IBA 11/2023 - 05/2009
12	Phenobarbital (Luminal)FDA Link 01/2024 - 05/2011
9	Estrogen ReceptorsIBA 01/2022 - 06/2007
9	Paclitaxel (Taxol)FDA LinkGeneric 10/2021 - 01/2012
8	human ERBB2 proteinIBA 03/2023 - 01/2016
8	Messenger RNA (mRNA)IBA 01/2021 - 10/2011
7	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2011
6	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 01/2012
6	ChemokinesIBA 03/2019 - 02/2011
5	ErbB Receptors (EGF Receptor)IBA 01/2023 - 01/2015
5	Trastuzumab (Herceptin)FDA Link 01/2022 - 01/2012
4	Estrogens (Estrogen)FDA Link 01/2021 - 07/2009
4	NRH - quinone oxidoreductase2IBA 01/2021 - 07/2009
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2014
4	Toll-Like Receptor 3IBA 01/2019 - 10/2011
4	Progesterone Receptors (Progesterone Receptor)IBA 01/2018 - 06/2007
4	ORALIT (ORS)IBA 07/2010 - 06/2010
3	Oxidoreductases (Dehydrogenase)IBA 01/2023 - 07/2009
3	Epirubicin (Ellence)FDA LinkGeneric 10/2021 - 11/2011
3	AnthracyclinesIBA 06/2021 - 05/2012
3	quinone (benzoquinone)IBA 01/2021 - 07/2009
3	Aromatase InhibitorsIBA 03/2020 - 12/2010
3	Long Noncoding RNAIBA 01/2019 - 01/2016
3	glutathione S-transferase M1IBA 01/2018 - 07/2009
2	EnzymesIBA 01/2024 - 01/2012
2	Androgen Receptors (Androgen Receptor)IBA 01/2024 - 03/2016
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2021 - 11/2011
2	QuinonesIBA 01/2021 - 07/2009
2	PlatinumIBA 01/2020 - 04/2013
2	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2018 - 06/2010
2	Phosphotransferases (Kinase)IBA 10/2016 - 05/2014
2	taxaneIBA 01/2016 - 01/2012
2	MicroRNAs (MicroRNA)IBA 04/2013 - 01/2013
2	Interleukin-6 (Interleukin 6)IBA 03/2013 - 07/2010
2	Tamoxifen FDA LinkGeneric 12/2010 - 06/2007
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 12/2010 - 11/2009
1	Methionine (L-Methionine)FDA Link 01/2024
1	Alanine Transaminase (SGPT)IBA 01/2024
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2023
1	Lidocaine (Xylocaine)FDA LinkGeneric 10/2023
1	Mannose (D-Mannose)IBA 03/2023
1	Hemagglutinins (Hemagglutinin)IBA 03/2023
1	Small Cytoplasmic RNAIBA 01/2023
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2023
1	Immunoconjugates (Immunoconjugate)IBA 01/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	CholesterolIBA 10/2022
1	famitinibIBA 01/2022
1	pertuzumabIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Epidermal Growth Factor (EGF)IBA 01/2022
1	neratinibIBA 01/2022
1	VaccinesIBA 01/2022
1	Lapatinib (GW572016)FDA Link 01/2022
1	130-nm albumin-bound paclitaxelIBA 01/2022
1	camrelizumabIBA 01/2022
1	Cancer VaccinesIBA 01/2022
1	CarcinogensIBA 01/2021
1	Vinorelbine (Navelbine)FDA LinkGeneric 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019
1	Immune Checkpoint InhibitorsIBA 01/2019
1	UbiquitinIBA 01/2019
1	Chemokine ReceptorsIBA 05/2016
1	KinesinsIBA 09/2015
1	Somatotropin Receptors (Growth Hormone Receptor)IBA 04/2015
1	Caspase 7IBA 03/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2014
1	ribosomal protein L39IBA 06/2014
1	Small Interfering RNA (siRNA)IBA 06/2014

Therapy/Procedure

21	Therapeutics 01/2024 - 06/2007
15	Drug Therapy (Chemotherapy) 03/2023 - 05/2009
13	Neoadjuvant Therapy 01/2024 - 01/2012
10	Adjuvant Chemotherapy 10/2021 - 11/2011
3	Segmental Mastectomy (Lumpectomy) 11/2022 - 01/2011
3	Mastectomy (Mammectomy) 11/2022 - 01/2011
3	Radiotherapy 01/2015 - 05/2009
1	Precision Medicine 01/2023
1	Immunotherapy 01/2020